Analysis of the role of COP9 Signalosome (CSN) subunits in K562; the first link between CSN and autophagy
<p>Abstract</p> <p>Background</p> <p>The COP9/signalosome (CSN) is a highly conserved eight subunit complex that, by deneddylating cullins in cullin-based E3 ubiquitin ligases, regulates protein degradation. Although studied in model human cell lines such as HeLa, very...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2009-04-01
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Series: | BMC Cell Biology |
Online Access: | http://www.biomedcentral.com/1471-2121/10/31 |