The structure of SV40 large T hexameric helicase in complex with AT-rich origin DNA

The structure of SV40 large T hexameric helicase in complex with AT-rich origin DNA

DNA replication is a fundamental biological process. The initial step in eukaryotic DNA replication is the assembly of the pre-initiation complex, including the formation of two head-to-head hexameric helicases around the replication origin. How these hexameric helicases interact with their origin d...

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Bibliographic Details
Main Authors: Dahai Gai, Damian Wang, Shu-Xing Li, Xiaojiang S Chen
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-12-01
Series:eLife
Subjects:
structural biology
DNA replication
APOBEC deaminase
Online Access:https://elifesciences.org/articles/18129

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