The structure of SV40 large T hexameric helicase in complex with AT-rich origin DNA
DNA replication is a fundamental biological process. The initial step in eukaryotic DNA replication is the assembly of the pre-initiation complex, including the formation of two head-to-head hexameric helicases around the replication origin. How these hexameric helicases interact with their origin d...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2016-12-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/18129 |