Early life adversity predicts brain-gut alterations associated with increased stress and mood

Early life adversity predicts brain-gut alterations associated with increased stress and mood

Alterations in the brain-gut system have been implicated in various disease states, but little is known about how early-life adversity (ELA) impacts development and adult health as mediated by brain-gut interactions. We hypothesize that ELA disrupts components of the brain-gut system, thereby increa...

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Bibliographic Details
Main Authors: Elena J.L. Coley, Emeran A. Mayer, Vadim Osadchiy, Zixi Chen, Vishvak Subramanyam, Yurui Zhang, Elaine Y. Hsiao, Kan Gao, Ravi Bhatt, Tien Dong, Priten Vora, Bruce Naliboff, Jonathan P. Jacobs, Arpana Gupta
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Neurobiology of Stress
Subjects:
Early life adversity
Brain-gut microbiome
Brain functional connectivity
Glutamatergic excitotoxicity
Perceived stress
Anxiety/depression
Online Access:http://www.sciencedirect.com/science/article/pii/S2352289521000564

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http://www.sciencedirect.com/science/article/pii/S2352289521000564

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