NUCLEOLIN AND NUCLEOPHOSMIN AS EXPECTED TARGETS FOR CATIONIC PEPTIDES, INDUCING TUMOR CELL APOPTOSIS

NUCLEOLIN AND NUCLEOPHOSMIN AS EXPECTED TARGETS FOR CATIONIC PEPTIDES, INDUCING TUMOR CELL APOPTOSIS

Multifunctional proteins nucleolin (NCL, C23) and nucleophosmin (NPM, B23) are the most abundant nucleolar phosphoproteins  with chaperone activities. Nucleolin is over-expressed also on tumor cell surface.   The proteins regulate the most of important cell functions, they  are considered now as th...

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Bibliographic Details
Main Authors: Анна Лушникова, Дарья Понкратова, Александр Костарев, Анна Рудакова, Сергей Андреев, Мария Барышникова
Format: Article
Language:English
Published: Cifra Publishing House 2018-08-01
Series:Journal of Bioinformatics and Genomics
Subjects:
cutaneous melanoma
cell lines
nucleolin
nucleophosmin
cationic peptides
apoptosis induction
Online Access:http://journal-biogen.org/index.php/jbg/article/view/14

Internet

http://journal-biogen.org/index.php/jbg/article/view/14

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