Processing of Candida albicans Ece1p Is Critical for Candidalysin Maturation and Fungal Virulence

Processing of Candida albicans Ece1p Is Critical for Candidalysin Maturation and Fungal Virulence

Candida albicans is an opportunistic fungal pathogen responsible for superficial and life-threatening infections in humans. During mucosal infection, C. albicans undergoes a morphological transition from yeast to invasive filamentous hyphae that secrete candidalysin, a 31-amino-acid peptide toxin re...

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Bibliographic Details
Main Authors: Jonathan P. Richardson, Selene Mogavero, David L. Moyes, Mariana Blagojevic, Thomas Kruger, Akash H. Verma, Bianca M. Coleman, Jacinto De La Cruz Diaz, Daniela Schulz, Nicole O. Ponde, Giulia Carrano, Olaf Kniemeyer, Duncan Wilson, Oliver Bader, Simona I. Enoiu, Jemima Ho, Nessim Kichik, Sarah L. Gaffen, Bernhard Hube, Julian R. Naglik, Gustavo H. Goldman
Format: Article
Language:English
Published: American Society for Microbiology 2018-01-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/9/1/e02178-17

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http://mbio.asm.org/cgi/content/full/9/1/e02178-17

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