Early Response Monitoring Following Radiation Therapy by Using [18F]FDG and [11C]Acetate PET in Prostate Cancer Xenograft Model with Metabolomics Corroboration

Early Response Monitoring Following Radiation Therapy by Using [18F]FDG and [11C]Acetate PET in Prostate Cancer Xenograft Model with Metabolomics Corroboration

We aim to characterize the metabolic changes associated with early response to radiation therapy in a prostate cancer mouse model by 2-deoxy-2-[18F]fluoro-d-glucose ([18F]FDG) and [11C]acetate ([11C]ACT) positron emission tomography, with nuclear magnetic resonance (NMR) metabolomics corroboration....

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Bibliographic Details
Main Authors: Yi-Hsiu Chung, Cheng-Kun Tsai, Chiun-Chieh Wang, Hsi-Mu Chen, Kuan-Ying Lu, Han Chiu, Yu-Chun Lin, Tzu-Chen Yen, Gigin Lin
Format: Article
Language:English
Published: MDPI AG 2017-11-01
Series:Molecules
Subjects:
[11C]Acetate
cancer metabolism
2-deoxy-2-[18F]fluoro-d-glucose
nuclear magnetic resonance
positron emission tomography
total lesion glycolysis
radiation therapy
Online Access:https://www.mdpi.com/1420-3049/22/11/1946

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https://www.mdpi.com/1420-3049/22/11/1946

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