T cells exacerbate Lyme borreliosis in TLR2-deficient mice

Infection of humans with the spirochete, Borrelia burgdorferi, causes Lyme borreliosis and can lead to clinical manifestations such as, arthritis, carditis and neurological conditions. Experimental infection of mice recapitulates many of these symptoms and serves as a model system for the investigat...

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Bibliographic Details
Main Authors: Carrie E. Lasky, Carmela Louise Pratt, Kinsey A Hilliard, Jacob J Jones, Charles Robert Brown
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-11-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00468/full