Association of polymorphisms in prolylcarboxypeptidase and chymase genes with essential hypertension in the Chinese Han population

Introduction: The prolylcarboxypeptidase (PRCP) gene encodes a membrane protein that acts on angiotensin II (Ang II) and kallikrein to release vasoactive peptides. The chymase (CMA1) gene is important for Ang II generation. Therefore, the two genes might be involved in the pathogenesis of essential...

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Bibliographic Details
Main Authors: Yanrui Wu, Hongju Yang, Benguan Yang, Ke Yang, Chunjie Xiao
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2013-09-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.1177/1470320312448949