Melatonin and Nitrones As Potential Therapeutic Agents for Stroke

Stroke is a disease of aging affecting millions of people worldwide, and recombinant tissue-type plasminogen activator (r-tPA) is the only treatment approved. However, r-tPA has a low therapeutic window and secondary effects which limit its beneficial outcome, urging thus the search for new more eff...

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Bibliographic Details
Main Authors: Alejandro Romero, Eva Ramos, Paloma Patiño, Maria J. Oset-Gasque, Francisco López-Muñoz, José Marco-Contelles, María I. Ayuso, Alberto Alcázar
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-11-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fnagi.2016.00281/full