The AGE-RAGE Axis: Implications for Age-Associated Arterial Diseases

The process of advanced glycation leads to the generation and accumulation of an heterogeneous class of molecules called advanced glycation endproducts, or AGEs. AGEs are produced to accelerated degrees in disorders such as diabetes, renal failure, inflammation, neurodegeneration, and in aging. Furt...

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Bibliographic Details
Main Authors: Laura M. Senatus, Ann Marie Schmidt
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fgene.2017.00187/full