High rates of de novo 15q11q13 inversions in human spermatozoa

High rates of de novo 15q11q13 inversions in human spermatozoa

<p>Abstract</p> <p>Low-Copy Repeats predispose the 15q11-q13 region to non-allelic homologous recombination. We have already demonstrated that a significant percentage of Prader-Willi syndrome (PWS) fathers have an increased susceptibility to generate 15q11q13 deletions in spermato...

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Bibliographic Details
Main Authors: Molina Òscar, Anton Ester, Vidal Francesca, Blanco Joan
Format: Article
Language:English
Published: BMC 2012-02-01
Series:Molecular Cytogenetics
Subjects:
Low Copy Repeats
Non-allelic Homologous Recombination
15q11q13 Inversions
Spermatozoa
Fluorescence <it>in situ </it>Hybridization
Online Access:http://www.molecularcytogenetics.org/content/5/1/11

Internet

http://www.molecularcytogenetics.org/content/5/1/11

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