Association between Insulin Monotherapy versus Insulin plus Metformin and the Risk of All-Cause Mortality and Other Serious Outcomes: A Retrospective Cohort Study.

AIMS:To determine if concomitant metformin reduced the risk of death, major adverse cardiac events (MACE), and cancer in people with type 2 diabetes treated with insulin. METHODS:For this retrospective cohort study, people with type 2 diabetes who progressed to insulin with or without metformin from...

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Bibliographic Details
Main Authors: Sarah E Holden, Sara Jenkins-Jones, Craig J Currie
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4859474?pdf=render