PhyloBot: A Web Portal for Automated Phylogenetics, Ancestral Sequence Reconstruction, and Exploration of Mutational Trajectories.

The method of phylogenetic ancestral sequence reconstruction is a powerful approach for studying evolutionary relationships among protein sequence, structure, and function. In particular, this approach allows investigators to (1) reconstruct and "resurrect" (that is, synthesize in vivo or...

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Bibliographic Details
Main Authors: Victor Hanson-Smith, Alexander Johnson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-07-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4966924?pdf=render