Cortical axons, isolated in channels, display activity-dependent signal modulation as a result of targeted stimulation

Mammalian cortical axons are extremely thin processes that are difficult to study as a result of their small diameter: they are too narrow to patch while intact, and super-resolution microscopy is needed to resolve single axons. We present a method for studying axonal physiology by pairing a high-de...

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Bibliographic Details
Main Authors: Marta K. Lewandowska, Miloš eRadivojević, David eJäckel, Jan eMüller, Andreas Reinhold Hierlemann
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-03-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2016.00083/full