Circulating Levels of the Soluble Receptor for AGE (sRAGE) during Escalating Oral Glucose Dosages and Corresponding Isoglycaemic i.v. Glucose Infusions in Individuals with and without Type 2 Diabetes

Circulating Levels of the Soluble Receptor for AGE (sRAGE) during Escalating Oral Glucose Dosages and Corresponding Isoglycaemic i.v. Glucose Infusions in Individuals with and without Type 2 Diabetes

Postprandial glucose excursions are postulated to increase the risk for diabetes complications via the production of advanced glycation end products (AGEs). The soluble receptor of AGEs (sRAGE) likely acts as a decoy receptor, mopping up AGEs, diminishing their capacity for pro-inflammatory and pro-...

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Bibliographic Details
Main Authors: Amelia K. Fotheringham, Jonatan I. Bagger, Danielle J. Borg, Domenica A. McCarthy, Jens J. Holst, Tina Vilsbøll, Filip K. Knop, Josephine M. Forbes
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Nutrients
Subjects:
RAGE
sRAGE
AGEs
type 2 diabetes mellitus
diabetes complications
metabolic alterations of T2DM
Online Access:https://www.mdpi.com/2072-6643/12/10/2928

Internet

https://www.mdpi.com/2072-6643/12/10/2928

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