A vascularized tumoroid model for human glioblastoma angiogenesis

Abstract Glioblastoma (GBM) angiogenesis is critical for tumor growth and recurrence, making it a compelling therapeutic target. Here, a disease-relevant, vascularized tumoroid in vitro model with stem-like features and stromal surrounds is reported. The model is used to recapitulate how individual...

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Bibliographic Details
Main Authors: Agavi Stavropoulou Tatla, Alexander W. Justin, Colin Watts, Athina E. Markaki
Format: Article
Language:English
Published: Nature Publishing Group 2021-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-98911-y