Src Family Kinases Mediate Betel Quid-Induced Oral Cancer Cell Motility and Could Be a Biomarker for Early Invasion in Oral Squamous Cell Carcinoma

Betel quid (BQ)-chewing oral cancer is a prevalent disease in many countries of Southeast Asia. Yet, the precise disease mechanism remains largely unknown. Here, we show that BQ extract-induced cell motility in three oral cancer cells (Ca9-22, SAS, and SCC9) presumably involves the Src family kinas...

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Bibliographic Details
Main Authors: Jeff Yi-Fu Chen, Chih-Chang Hung, Kai-Lieh Huang, Yi-Ting Chen, Shyun-Yeu Liu, Wei-Fan Chiang, Hau-Ren Chen, Ching-Yu Yen, Yu-Jen Wu, Jenq-Yuh Ko, Yuh-Shan Jou
Format: Article
Language:English
Published: Elsevier 2008-12-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S147655860880084X