Examining the virulence of Candida albicans transcription factor mutants using Galleria mellonella and mouse infection models

Examining the virulence of Candida albicans transcription factor mutants using Galleria mellonella and mouse infection models

The aim of the present study was to identify C. albicans transcription factors (TF) involved in virulence. Although mice are considered the gold-standard model to study fungal virulence, mini-host infection models have been increasingly used. Here, barcoded TF mutants were first screened in mice by...

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Bibliographic Details
Main Authors: Sara eAmorim-Vaz, Eric eDelarze, Francoise eIscher, Dominique eSanglard, Alix Thérèse Coste
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-05-01
Series:Frontiers in Microbiology
Subjects:
Candida albicans
Mice
Transcription Factors
Virulence
Galleria mellonella
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00367/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00367/full

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