The interleukin-33 receptor contributes to pulmonary responses to ozone in male mice: role of the microbiome

The interleukin-33 receptor contributes to pulmonary responses to ozone in male mice: role of the microbiome

Abstract Background Interleukin-33 is released in the airways following acute ozone exposure and has the ability to cause airway hyperresponsiveness, a defining feature of asthma. Ozone causes greater airway hyperresponsiveness in male than female mice. Moreover, sex differences in the gut microbiom...

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Bibliographic Details
Main Authors: David I. Kasahara, Jeremy E. Wilkinson, Youngji Cho, Aline P. Cardoso, Curtis Huttenhower, Stephanie A. Shore
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Respiratory Research
Subjects:
IL-33
Sex differences
Airway responsiveness
Neutrophil
Interleukin-5
Online Access:http://link.springer.com/article/10.1186/s12931-019-1168-x

Internet

http://link.springer.com/article/10.1186/s12931-019-1168-x

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