JNK Inactivation Induces Polyploidy and Drug-Resistance in Coronarin D-Treated Osteosarcoma Cells

Inhibition of proliferating cells is a critical strategy for cancer therapy. In this study, we demonstrated that coronarin D, a natural component extracted from the rhizomes of Hedychium coronarium, significantly suppressed the proliferation of osteosarcoma cells. The treatment with coronarin D resu...

Full description

Bibliographic Details
Main Authors: Chang-Te Hsu, Yi-Fu Huang, Chen-Pu Hsieh, Chia-Chieh Wu, Tai-Shan Shen
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:Molecules
Subjects:
JNK
Online Access:http://www.mdpi.com/1420-3049/23/9/2121