Mesenchymal stem cell-derived exosome miR-542-3p suppresses inflammation and prevents cerebral infarction

Mesenchymal stem cell-derived exosome miR-542-3p suppresses inflammation and prevents cerebral infarction

Abstract Background Cerebral infarction ranks as the second leading cause of disability and death globally, and inflammatory response of glial cells is the main cause of brain damage during cerebral infarction. Methods Studies have shown that mesenchymal stem cells (MSCs) can secrete exosomes and co...

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Bibliographic Details
Main Authors: Guofeng Cai, Guoliang Cai, Haichun Zhou, Zhe Zhuang, Kai Liu, Siying Pei, Yanan Wang, Hong Wang, Xin Wang, Shengnan Xu, Cheng Cui, Manchao Sun, Sihui Guo, Kunping Jia, Xiuzhen Wang, Dianquan Zhang
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Stem Cell Research & Therapy
Subjects:
Cerebral infarction
Inflammation
Exosome
MicroRNA
MSC
Online Access:https://doi.org/10.1186/s13287-020-02030-w

Internet

https://doi.org/10.1186/s13287-020-02030-w

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