Flutamide ameliorates uterine decidualization and angiogenesis in the mouse hyperandrogenemia model during mid-pregnancy.

Flutamide ameliorates uterine decidualization and angiogenesis in the mouse hyperandrogenemia model during mid-pregnancy.

<h4>Background/aim</h4>Patients with polycystic ovary syndrome (PCOS), characterized by anovulation, hyperandrogenemia and polycystic ovaries, are still vulnerable to undergo recurrent pregnancy loss and premature labor even though the ovulatory process is pharmacologically recovered. Ho...

Full description

Bibliographic Details
Main Authors:	Han Gong, Weiqi Wu, Jingjie Xu, Dainan Yu, Bo Qiao, Hui Liu, Bei Yang, Yuezhen Li, Yan Ling, Haibin Kuang
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2019-01-01
Series:	PLoS ONE
Online Access:	https://doi.org/10.1371/journal.pone.0217095

Similar Items

The regulation of ovary and conceptus on the uterine natural killer cells during early pregnancy
by: Han Gong, et al.
Published: (2017-09-01)

Human Uterine Decidual NK Cells in Women with a History of Early Pregnancy Enhance Angiogenesis and Trophoblast Invasion
by: Ningyi Jia, et al.
Published: (2020-01-01)

Adrenal myelolipoma with hyperandrogenemia and schizophrenia
by: Liu N, et al.
Published: (2018-02-01)

Erratum to “Human Uterine Decidual NK Cells in Women with a History of Early Pregnancy Enhance Angiogenesis and Trophoblast Invasion”
by: Ningyi Jia, et al.
Published: (2020-01-01)

The impact of obesity on hyperandrogenemia in Korean girls
by: Min Jae Kang, et al.
Published: (2016-12-01)

Hyperandrogenemia due to ingestion of Butea superba
by: Kamon Chaiyasit, et al.
Published: (2012-01-01)

HB-EGF Ameliorates Oxidative Stress-Mediated Uterine Decidualization Damage
by: Hai-Fan Yu, et al.
Published: (2019-01-01)

Cardiometabolic consequences of maternal hyperandrogenemia in male offspring
by: Yvonne Zuchowski, et al.
Published: (2021-07-01)

Comparison of the Therapeutic Effect of Combination of Flutamide-Cyproterone Compound with Flutamide-Doxycycline in Severe Female Acne
by: Hasan Edalatkhah, et al.
Published: (2018-07-01)

Uterine glands coordinate on-time embryo implantation and impact endometrial decidualization for pregnancy success
by: Andrew M. Kelleher, et al.
Published: (2018-06-01)

The Effect of Flutamide on Ovulation Induction in PCOS Patients
by: Tahereh Madani, et al.
Published: (2012-04-01)

Effects of testosterone and flutamide on reproduction in Brachionus calyciflorus
by: Jian Tian, et al.
Published: (2017-07-01)

Effects of the anti-androgen flutamide on their descent of the testis
by: Kassim, Normadiah M.
Published: (1996)

Metastatin as a Marker for Hyperandrogenemia in Iraqi Women with Polycystic Ovary Syndrome
by: Manal Madany Abdalqader, et al.
Published: (2020-01-01)

Testosterone/Epitestosterone Ratios—Further Hints to Explain Hyperandrogenemia in Children with Autism
by: Benedikt Gasser, et al.
Published: (2021-02-01)

Gene Variants Are Associated with PCOS Susceptibility and Hyperandrogenemia in Young Korean Women
by: Do Kyeong Song, et al.
Published: (2014-08-01)

Lipid Profile in Adolescent Girls with Type 1 Diabetes Mellitus and Hyperandrogenemia
by: Agnieszka Zachurzok, et al.
Published: (2016-01-01)

Unique and independent role of the GABAB1 subunit in embryo implantation and uterine decidualization in mice
by: Wenhao Chen, et al.
Published: (2021-01-01)

TGFβ superfamily signaling and uterine decidualization
by: Nan Ni, et al.
Published: (2017-10-01)

Phenotypic variability of hyperandrogenemia in females heterozygous for CYP21A2 mutations
by: Vassos Neocleous, et al.
Published: (2014-01-01)

Flutamide-induced alterations in transcriptional profiling of neonatal porcine ovaries
by: Katarzyna Knapczyk-Stwora, et al.
Published: (2019-04-01)

Endothelial Jagged1 Antagonizes Dll4/Notch Signaling in Decidual Angiogenesis during Early Mouse Pregnancy
by: Nicole M. Marchetto, et al.
Published: (2020-09-01)

Hyperandrogenemia in polycystic ovary syndrome: exploration of the role of free testosterone and androstenedione in metabolic phenotype.
by: Elisabeth Lerchbaum, et al.
Published: (2014-01-01)

A case of postmenopausal ovarian hyperandrogenemia diagnosed only by selective catheterization of ovarian vein
by: Mehmet Musa Aslan, et al.
Published: (2018-09-01)

The uterine expression of <it>SEC63 </it>gene is up-regulated at implantation sites in association with the decidualization during the early pregnancy in mice
by: Su Ren-wei, et al.
Published: (2009-02-01)

ROLES OF HAND2 TRANSCRIPTION FACTOR IN UTERINE RECEPTIVITY AND DECIDUALIZATION
by: Doan, Huyen Van
Published: (2013)

Folate Deficiency Could Restrain Decidual Angiogenesis in Pregnant Mice
by: Yanli Li, et al.
Published: (2015-08-01)

Postmenopausal mild hirsutism and hyperandrogenemia due to granulosa cell tumor of the ovary: a case report
by: Mulat Adefris, et al.
Published: (2017-08-01)

Assessment of embryotoxicity of the antiandrogenic drugs flutamide and bicalutamide in zebrafish (Danio rerio)
by: Holmlund, Josefin
Published: (2020)

Coenzyme Q 10 Abrogates Flutamide-induced Hepatotoxicity in Albino Rats
by: Elias Adikwu, et al.
Published: (2019-10-01)

Voltammetric study of ds-DNA–flutamide interaction at carbon paste electrode
by: Pradeep K. Brahman, et al.
Published: (2016-11-01)

Flutamide-Induced Cytotoxicity and Oxidative Stress in an In Vitro Rat Hepatocyte System
by: Abdullah Al Maruf, et al.
Published: (2014-01-01)

The assessment of the angiogenesis in the uterine cervix carcinogenesis
by: Doina Lucia Francu, et al.
Published: (2008-05-01)

Disordered IL-33/ST2 activation in decidualizing stromal cells prolongs uterine receptivity in women with recurrent pregnancy loss.
by: Madhuri S Salker, et al.
Published: (2012-01-01)

The role of decidual T lymphocytes in human pregnancy
by: Scaife, Paula Juliet
Published: (2005)

Risk of Insulin Resistance and Metabolic Syndrome in Women with Hyperandrogenemia: A Comparison between PCOS Phenotypes and Beyond
by: Valentin Borzan, et al.
Published: (2021-02-01)

Postmenopausal mild hirsutism and hyperandrogenemia due to ovarian Sertoli-Leydig cell tumor: A case report
by: Dan Chen, et al.
Published: (2020-04-01)

Embryos from polycystic ovary syndrome patients with hyperandrogenemia reach morula stage faster than controls
by: Neil Ryan Chappell, M.D., et al.
Published: (2020-09-01)

Inhibition of IL-6 signaling pathway by curcumin in uterine decidual cells.
by: Y Sangeeta Devi, et al.
Published: (2015-01-01)

Thyroid hormones affect decidualization and angiogenesis in the decidua and metrial gland of rats
by: Cíntia A. Souza, et al.

Cannot write session to /tmp/vufind_sessions/sess_4mujbi8ipn2emqdst82h1tclsv