Flutamide ameliorates uterine decidualization and angiogenesis in the mouse hyperandrogenemia model during mid-pregnancy.

<h4>Background/aim</h4>Patients with polycystic ovary syndrome (PCOS), characterized by anovulation, hyperandrogenemia and polycystic ovaries, are still vulnerable to undergo recurrent pregnancy loss and premature labor even though the ovulatory process is pharmacologically recovered. Ho...

Full description

Bibliographic Details
Main Authors: Han Gong, Weiqi Wu, Jingjie Xu, Dainan Yu, Bo Qiao, Hui Liu, Bei Yang, Yuezhen Li, Yan Ling, Haibin Kuang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0217095