CDC25 Inhibition in Acute Myeloid Leukemia–A Study of Patient Heterogeneity and the Effects of Different Inhibitors

CDC25 Inhibition in Acute Myeloid Leukemia–A Study of Patient Heterogeneity and the Effects of Different Inhibitors

Cell division cycle 25 (CDC25) protein phosphatases regulate cell cycle progression through the activation of cyclin-dependent kinases (CDKs), but they are also involved in chromatin modulation and transcriptional regulation. CDC25 inhibition is regarded as a possible therapeutic strategy for the tr...

Full description

Bibliographic Details
Main Authors: Annette K. Brenner, Håkon Reikvam, Kristin Paulsen Rye, Karen Marie Hagen, Antonio Lavecchia, Øystein Bruserud
Format: Article
Language:English
Published: MDPI AG 2017-03-01
Series:Molecules
Subjects:
CDC25 inhibitors
acute myeloid leukemia
gene expression
cytogenetics
leukemic cell differentiation
Online Access:http://www.mdpi.com/1420-3049/22/3/446

Internet

http://www.mdpi.com/1420-3049/22/3/446

Similar Items