Computational design of improved standardized chemotherapy protocols for grade II oligodendrogliomas.

Computational design of improved standardized chemotherapy protocols for grade II oligodendrogliomas.

Here we put forward a mathematical model describing the response of low-grade (WHO grade II) oligodendrogliomas (LGO) to temozolomide (TMZ). The model describes the longitudinal volumetric dynamics of tumor response to TMZ of a cohort of 11 LGO patients treated with TMZ. After finding patient-specif...

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Bibliographic Details
Main Authors: Víctor M Pérez-García, Luis E Ayala-Hernández, Juan Belmonte-Beitia, Philippe Schucht, Michael Murek, Andreas Raabe, Juan Sepúlveda
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-07-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1006778

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https://doi.org/10.1371/journal.pcbi.1006778

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