Immune Checkpoint Inhibitor-Associated Cardiotoxicity: Current Understanding on Its Mechanism, Diagnosis and Management

Immune Checkpoint Inhibitor-Associated Cardiotoxicity: Current Understanding on Its Mechanism, Diagnosis and Management

Immune checkpoint inhibitors (ICIs) that target cytotoxic T lymphocyte antigen 4, programmed cell death-1, and PD-ligand 1 have revolutionized cancer treatment, achieving unprecedented efficacy in multiple malignancies. ICIs are increasingly being used in early cancer settings and in combination wit...

Full description

Bibliographic Details
Main Authors: Yu-Wen Zhou, Ya-Juan Zhu, Man-Ni Wang, Yao Xie, Chao-Yue Chen, Tao Zhang, Fan Xia, Zhen-Yu Ding, Ji-Yan Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Pharmacology
Subjects:
immune checkpoint inhibitors
cardiotoxicity
myocarditis
pericarditis
cytotoxic T lymphocyte-associated antigen-4
programmed cell death protein 1
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.01350/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.01350/full

Similar Items