Interaction between human osteosarcoma and mesenchymal stem cells via an interleukin-8 signaling loop in the tumor microenvironment
Abstract Background Osteosarcoma (OS) is the representative primary malignant bone tumor with the highest incidence. It is known that malignant phenotypes of OS, such as proliferation, invasion, and metastasis, are significantly influenced not only by characteristics of the tumor itself, but also by...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-04-01
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Series: | Cell Communication and Signaling |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12964-018-0225-2 |