Effects of skeletal unloading on the antibody repertoire of tetanus toxoid and/or CpG treated C57BL/6J mice.

Spaceflight affects the immune system, but the effects on the antibody repertoire, responsible for humoral immunity, has not been well explored. In particular, the complex gene assembly and expression process; including mutations, might make this process vulnerable. Complementarity determining regio...

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Bibliographic Details
Main Authors: Trisha A Rettig, Bailey A Bye, Nina C Nishiyama, Savannah Hlavacek, Claire Ward, Michael J Pecaut, Stephen K Chapes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0210284