Eicosanoids as endogenous regulators of leptin release and lipolysis by mouse adipose tissue in primary culture

Prostaglandin E2 (PGE2) stimulated leptin release over a 24-h incubation of mouse adipose tissue in primary culture. The maximal stimulation of leptin release was seen with 100 nm PGE2. The role of endogenous eicosanoids in the regulation of lipolysis and leptin formation was examined in the presenc...

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Bibliographic Details
Main Authors: John N. Fain, Charles W. Leffler, Suleiman W. Bahouth
Format: Article
Language:English
Published: Elsevier 2000-10-01
Series:Journal of Lipid Research
Subjects:
CPA
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520320034