Spatial Memory Dysfunction Induced by Vitamin C Deficiency Is Associated with Changes in Monoaminergic Neurotransmitters and Aberrant Synapse Formation

Vitamin C (vitC) is important in the developing brain, acting both as an essential antioxidant and as co-factor in the synthesis and metabolism of monoaminergic neurotransmitters. In guinea pigs, vitC deficiency results in increased oxidative stress, reduced hippocampal volume and neuronal numbers,...

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Bibliographic Details
Main Authors: Stine Normann Hansen, Anne Marie V. Schou-Pedersen, Jens Lykkesfeldt, Pernille Tveden-Nyborg
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:Antioxidants
Subjects:
Online Access:http://www.mdpi.com/2076-3921/7/7/82