An optimised GAS-pharyngeal cell biofilm model

Abstract Group A Streptococcus (GAS) causes 700 million infections and accounts for half a million deaths per year. Biofilm formation has been implicated in both pharyngeal and dermal GAS infections. In vitro, plate-based assays have shown that several GAS M-types form biofilms, and multiple GAS vir...

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Bibliographic Details
Main Authors: Heema K. N. Vyas, Jason D. McArthur, Martina L. Sanderson-Smith
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-87377-7