Increased fibroblast telomerase expression precedes myofibroblast α-smooth muscle actin expression in idiopathic pulmonary fibrosis

Increased fibroblast telomerase expression precedes myofibroblast α-smooth muscle actin expression in idiopathic pulmonary fibrosis

OBJECTIVE: This study sought to identify the relationship between fibroblast telomerase expression, myofibroblasts, and telomerase-mediated regulatory signals in idiopathic pulmonary fibrosis. METHODS: Thirty-four surgical lung biopsies, which had been obtained from patients with idiopathic pulmonar...

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Bibliographic Details
Main Authors: Daniel Reis Waisberg, Edwin Roger Parra, João Valente Barbas-Filho, Sandra Fernezlian, Vera Luiza Capelozzi
Format: Article
Language:English
Published: Faculdade de Medicina / USP 2012-09-01
Series:Clinics
Subjects:
Telomerase
Fibroblasts
α-smooth Muscle Actin
Interleukin-4
Idiopathic Pulmonary Fibrosis
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322012000900010&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322012000900010&lng=en&tlng=en

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