Chemopreventive Agent 3,3′-Diindolylmethane Inhibits MDM2 in Colorectal Cancer Cells

Chemopreventive Agent 3,3′-Diindolylmethane Inhibits MDM2 in Colorectal Cancer Cells

3,3′-Diindolylmethane (DIM) is a naturally derived chemopreventive compound. It comes from glucobrassicin, an indole glucosinolate enriched in cruciferous vegetables, and is formed in the acidic environment of the stomach after ingestion. Mouse double minute 2 homolog (MDM2) is an important, multi-f...

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Bibliographic Details
Main Authors: Xiang Gao, Jingwen Liu, Kwang Bog Cho, Samanthreddy Kedika, Bin Guo
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:International Journal of Molecular Sciences
Subjects:
3,3′-Diindolylmethane
MDM2
colorectal cancer
p53
cancer prevention
Online Access:https://www.mdpi.com/1422-0067/21/13/4642

Internet

https://www.mdpi.com/1422-0067/21/13/4642

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