A Metabolic Checkpoint for the Yeast-to-Hyphae Developmental Switch Regulated by Endogenous Nitric Oxide Signaling

Summary: The yeast Candida albicans colonizes several sites in the human body and responds to metabolic signals in commensal and pathogenic states. The yeast-to-hyphae transition correlates with virulence, but how metabolic status is integrated with this transition is incompletely understood. We use...

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Bibliographic Details
Main Authors: Barbara Koch, Adele A. Barugahare, Tricia L. Lo, Cheng Huang, Ralf B. Schittenhelm, David R. Powell, Traude H. Beilharz, Ana Traven
Format: Article
Language:English
Published: Elsevier 2018-11-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S221112471831684X