IL2RA/CD25 gene polymorphisms: uneven association with multiple sclerosis (MS) and type 1 diabetes (T1D).

IL2RA/CD25 gene polymorphisms: uneven association with multiple sclerosis (MS) and type 1 diabetes (T1D).

BACKGROUND: IL-2 receptor (IL2R) alpha is the specific component of the high affinity IL2R system involved in the immune response and in the control of autoimmunity. METHODS AND RESULTS: Here we perform a replication and fine mapping of the IL2RA gene region analyzing 3 SNPs previously associated wi...

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Main Authors: Antonio Alcina, María Fedetz, Dorothy Ndagire, Oscar Fernández, Laura Leyva, Miguel Guerrero, María M Abad-Grau, Carmen Arnal, Concepción Delgado, Miguel Lucas, Guillermo Izquierdo, Fuencisla Matesanz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2607550?pdf=render

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http://europepmc.org/articles/PMC2607550?pdf=render

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