FRAS1-related extracellular matrix 3 (FREM3) single-nucleotide polymorphism effects on gene expression, amygdala reactivity and perceptual processing speed

The A allele of the Fras1-related extracellular matrix protein 3 (FREM3) rs7676614 single nucleotide polymorphism (SNP) was linked to major depressive disorder (MDD) in an early genome-wide association study (GWAS), and to symptoms of psychomotor retardation in a follow-up investigation. In line wit...

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Bibliographic Details
Main Authors: Yuliya eNikolova, Swetha P Iruku, Chien-Wei eLin, Emily Drabant Conley, Rachel ePuralewski, Beverly eFrench, Ahmad R Hariri, Etienne eSibille
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-09-01
Series:Frontiers in Psychology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fpsyg.2015.01377/full