Mathematical models for sleep-wake dynamics: comparison of the two-process model and a mutual inhibition neuronal model.

Sleep is essential for the maintenance of the brain and the body, yet many features of sleep are poorly understood and mathematical models are an important tool for probing proposed biological mechanisms. The most well-known mathematical model of sleep regulation, the two-process model, models the s...

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Bibliographic Details
Main Authors: Anne C Skeldon, Derk-Jan Dijk, Gianne Derks
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4118955?pdf=render