Treatment Strategies for ARID1A-Deficient Ovarian Clear Cell Carcinoma

Treatment Strategies for ARID1A-Deficient Ovarian Clear Cell Carcinoma

Ovarian clear cell carcinoma (OCCC) is a histological subtype of ovarian cancer that is more frequent in Asian countries (~25% of ovarian cancers) than in US/European countries (less than 10%). OCCC is refractory to conventional platinum-based chemotherapy, which is effective against high-grade sero...

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Bibliographic Details
Main Authors: Kazuaki Takahashi, Masataka Takenaka, Aikou Okamoto, David D. L. Bowtell, Takashi Kohno
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cancers
Subjects:
ovarian clear cell carcinoma
ARID1A
synthetic lethality
gemcitabine
molecular targeted therapy
precision medicine
Online Access:https://www.mdpi.com/2072-6694/13/8/1769

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https://www.mdpi.com/2072-6694/13/8/1769

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