The dark side of ferroptosis in pancreatic cancer

The dark side of ferroptosis in pancreatic cancer

Drug-induced ferroptosis, an iron-dependent regulatory necrosis, has been proposed for the therapy of pancreatic ductal adenocarcinoma. However, genetically engineered mouse models have revealed that high-iron diets or deletion of pancreatic GPX4 (a key repressor of ferroptosis) accelerate the devel...

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Bibliographic Details
Main Authors: Jiao Liu, Enyong Dai, Rui Kang, Guido Kroemer, Daolin Tang
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:OncoImmunology
Subjects:
dna damage
damp
ferroptosis
immunity
macrophages
pancreatic cancer
pancreatitis
sting1
Online Access:http://dx.doi.org/10.1080/2162402X.2020.1868691

Internet

http://dx.doi.org/10.1080/2162402X.2020.1868691

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