Crucial roles of the protein kinases MK2 and MK3 in a mouse model of glomerulonephritis.

Crucial roles of the protein kinases MK2 and MK3 in a mouse model of glomerulonephritis.

Elevated mitogen-activated protein kinase p38 (p38 MAPK) signaling has been implicated in various experimental and human glomerulopathies, and its inhibition has proven beneficial in animal models of these diseases. p38 MAPK signaling is partially mediated through MK2 and MK3, two phylogenetically r...

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Bibliographic Details
Main Authors: Adam J Guess, Rose Ayoob, Melinda Chanley, Joshua Manley, Mariana M Cajaiba, Shipra Agrawal, Ruma Pengal, Amy L Pyle, Brian Becknell, Jeffrey B Kopp, Natalia Ronkina, Matthias Gaestel, Rainer Benndorf, William E Smoyer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3553169?pdf=render

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http://europepmc.org/articles/PMC3553169?pdf=render

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