Estabelecimento de condições para ensaio de dissolução de cápsulas de cinarizina empregando planejamento fatorial

This work describes the establishment of dissolution test conditions for 75 mg cinnarizine capsules using a multivariate approach. A 2³ full factorial design was carried out to achieve the best conditions and HCl 0.1 mol L-1 as dissolution medium, basket as apparatus at 100 rpm and collect time at 3...

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Bibliographic Details
Main Authors: Patrícia Alves Franco Gehring, Olímpia Maria Martins Santos, Gislaine Ribeiro Pereira, Magali Benjamim de Araújo, Rudy Bonfilio
Format: Article
Language:English
Published: Sociedade Brasileira de Química 2011-01-01
Series:Química Nova
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422011000300017&lng=en&tlng=en