Unlocking Doors without Keys: Activation of Src by Truncated C-terminal Intracellular Receptor Tyrosine Kinases Lacking Tyrosine Kinase Activity

One of the best examples of the renaissance of Src as an open door to cancer has been the demonstration that just five min of Src activation is sufficient for transformation and also for induction and maintenance of cancer stem cells [1]. Many tyrosine kinase receptors, through the binding of their...

Full description

Bibliographic Details
Main Authors: Belén Mezquita, Pau Mezquita, Montserrat Pau, Jovita Mezquita, Cristóbal Mezquita
Format: Article
Language:English
Published: MDPI AG 2014-02-01
Series:Cells
Subjects:
KIT
Online Access:http://www.mdpi.com/2073-4409/3/1/92