Unlocking Doors without Keys: Activation of Src by Truncated C-terminal Intracellular Receptor Tyrosine Kinases Lacking Tyrosine Kinase Activity
One of the best examples of the renaissance of Src as an open door to cancer has been the demonstration that just five min of Src activation is sufficient for transformation and also for induction and maintenance of cancer stem cells [1]. Many tyrosine kinase receptors, through the binding of their...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2014-02-01
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Series: | Cells |
Subjects: | |
Online Access: | http://www.mdpi.com/2073-4409/3/1/92 |