Entropic stabilization of proteins and its proteomic consequences.
Evolutionary traces of thermophilic adaptation are manifest, on the whole-genome level, in compositional biases toward certain types of amino acids. However, it is sometimes difficult to discern their causes without a clear understanding of underlying physical mechanisms of thermal stabilization of...
Format: | Article |
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Language: | English |
Published: |
Public Library of Science (PLoS)
2005-09-01
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Series: | PLoS Computational Biology |
Online Access: | http://dx.doi.org/10.1371/journal.pcbi.0010047 |