Fibrillar beta-amyloid peptide Aβ<sub>1–40 </sub>activates microglial proliferation via stimulating TNF-α release and H<sub>2</sub>O<sub>2 </sub>derived from NADPH oxidase: a cell culture study
<p>Abstract</p> <p>Background</p> <p>Alzheimer's disease is characterized by the accumulation of neuritic plaques, containing activated microglia and β-amyloid peptides (Aβ). Fibrillar Aβ can activate microglia, resulting in production of toxic and inflammatory med...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2006-09-01
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| Series: | Journal of Neuroinflammation |
| Online Access: | http://www.jneuroinflammation.com/content/3/1/24 |