Dietary Emulsifiers Directly Impact Adherent-Invasive E. coli Gene Expression to Drive Chronic Intestinal Inflammation

Dietary Emulsifiers Directly Impact Adherent-Invasive E. coli Gene Expression to Drive Chronic Intestinal Inflammation

Summary: Dietary emulsifiers carboxymethylcellulose (CMC) and polysorbate-80 (P80) disturb gut microbiota, promoting chronic inflammation. Mice with minimal microbiota are protected against emulsifiers’ effects, leading us to hypothesize that these compounds might provoke select pathobionts to promo...

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Bibliographic Details
Main Authors: Emilie Viennois, Alexis Bretin, Philip E. Dubé, Alexander C. Maue, Charlène J.G. Dauriat, Nicolas Barnich, Andrew T. Gewirtz, Benoit Chassaing
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:Cell Reports
Subjects:
emulsifier
adherent-invasive Escherichia coli
intestinal inflammation
flagellin
microbiota
pathobiont
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720312183

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http://www.sciencedirect.com/science/article/pii/S2211124720312183

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