Identification of Tumor Necrosis Factor-Alpha (TNF-α) Inhibitor in Rheumatoid Arthritis Using Network Pharmacology and Molecular Docking

Identification of Tumor Necrosis Factor-Alpha (TNF-α) Inhibitor in Rheumatoid Arthritis Using Network Pharmacology and Molecular Docking

Background: This study aimed to investigate the molecular mechanism of Radix Paeoniae Alba (white peony, WP) in treating immune inflammatory diseases of rheumatoid arthritis (RA) and tumor necrosis factor-alpha (TNF-α) inhibitors (TNFis) by using network pharmacology and molecular docking.Methods: I...

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Bibliographic Details
Main Authors: Liang Liang Bai, Hao Chen, Peng Zhou, Jun Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Pharmacology
Subjects:
immune inflammatory
rheumatoid arthritis
Paeonia lactiflora Pallas
network pharmacology
molecular docking
tumor necrosis factor-alpha inhibitor
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.690118/full

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https://www.frontiersin.org/articles/10.3389/fphar.2021.690118/full

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