Molecular Diversity via Tetrasubstituted Alkenes Containing a Barbiturate Motif: Synthesis and Biological Activity

Molecular Diversity via Tetrasubstituted Alkenes Containing a Barbiturate Motif: Synthesis and Biological Activity

The synthesis of a molecularly diverse library of tetrasubstituted alkenes containing a barbiturate motif is described. Base-induced condensation of <i>N</i><sup>1</sup>-substituted pyrimidine-2,4,6(1<i>H</i>,3<i>H</i>,5<i>H</i>)-triones wi...

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Bibliographic Details
Main Authors: Ahmed Al-Sheikh, Masuma Begum, Bian Zhang, Richard A. Lewis, Nicholas E. E. Allenby, Paul G. Waddell, Bernard T. Golding
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Molecules
Subjects:
molecular diversity
barbiturate template
antifungal
antibacterial
trifluoroethanol
Online Access:https://www.mdpi.com/1420-3049/25/24/5868

Internet

https://www.mdpi.com/1420-3049/25/24/5868

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