Reciprocal Inflammatory Signaling Between Intestinal Epithelial Cells and Adipocytes in the Absence of Immune Cells

Visceral fat accumulation as observed in Crohn's disease and obesity is linked to chronic gut inflammation, suggesting that accumulation of gut adipocytes can trigger local inflammatory signaling. However, direct interactions between intestinal epithelial cells (IECs) and adipocytes have not be...

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Bibliographic Details
Main Authors: Yu Takahashi, Shintaro Sato, Yosuke Kurashima, Chen-Yi Lai, Makoto Otsu, Mikio Hayashi, Takayuki Yamaguchi, Hiroshi Kiyono
Format: Article
Language:English
Published: Elsevier 2017-09-01
Series:EBioMedicine
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S235239641730302X