Conserved immunomodulatory transcriptional networks underlie antipsychotic-induced weight gain

Abstract Although antipsychotics, such as olanzapine, are effective in the management of psychiatric conditions, some patients experience excessive antipsychotic-induced weight gain (AIWG). To illuminate pathways underlying AIWG, we compared baseline blood gene expression profiles in two cohorts of...

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Bibliographic Details
Main Authors: Rizaldy C. Zapata, Besma S. Chaudry, Mariela Lopez Valencia, Dinghong Zhang, Scott A. Ochsner, Neil J. McKenna, Olivia Osborn
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-021-01528-y